Chemical synthesis of peptide libraries
Identifieur interne : 003010 ( Main/Exploration ); précédent : 003009; suivant : 003011Chemical synthesis of peptide libraries
Auteurs : Ferenc Sebestyén ; Gábor Dib ; Attila Kovács [Hongrie] ; Árpd FurkuaSource :
- Bioorganic & Medicinal Chemistry Letters [ 0960-894X ] ; 1993.
Abstract
The efficiency of the “portioning-mixing” method is demonstrated by the synthesis of more than one million hexapeptides in 5 days. An example is described to illustrate the possibility of completion of partial peptide libraries. Our method is also shown to be suitable to carry out binary peptide synthesis. In addition, a new screening method is outlined based on specific interaction of peptides with living cells.
Url:
DOI: 10.1016/S0960-894X(01)80223-7
Affiliations:
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